Cromolyn (sodium salt hydrate)

Cromolyn is a chromone complex that acts as a mast cell stabilizer, preventing the release of histamine. Its mechanism of action is thought to involve an interference with the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions.Formal Name: 5,5'-((2-hydroxypropane-1,3-diyl)bis(oxy))bis(4-oxo-4H-chromene-2-carboxylate) sodium hydrate. Molecular Formula: C23H14O11 . 2Na [XH2O]. Formula Weight: 512.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 222, 239, 326 nm. SMILES: OC(COC1=C(C(OC(C([O-])=O)=C2)=CC=C1)C2=O)COC3=C(C(OC(C([O-])=O)=C4)=CC=C3)C4=O.[Na+].[Na+].O. InChi Code: InChI=1S/C23H16O11.2Na.H2O/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30,,,/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30),,,1H2/q,2*+1,/p-2. InChi Key: LIZBBKUQXFWZCB-UHFFFAOYSA-L.