CPI-444

CPI-444 is an antagonist of the adenosine A2A receptor. It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.Formal Name: 7-(5-methyl-2-furanyl)-3-[[6-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]-2-pyridinyl]methyl]-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine. CAS Number: 1202402-40-1. Synonyms: Ciforadenant. Molecular Formula: C20H21N7O3. Formula Weight: 407.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml. lambdamax: 321, 352 nm. SMILES: CC1=CC=C(O1)C2=C3C(N(CC4=CC=CC(CO[C@@H]5COCC5)=N4)N=N3)=NC(N)=N2. InChi Code: InChI=1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13-3-2-4-14(22-13)10-29-15-7-8-28-11-15/h2-6,15H,7-11H2,1H3,(H2,21,23,24)/t15-/m0/s1. InChi Key: KURQKNMKCGYWRJ-HNNXBMFYSA-N.