CPI-268456

CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 (IC50 = 50 = <0.5 µM).Formal Name: (4S)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-isoxazolo[5,4-d][2]benzazepine-4-acetamide. CAS Number: 1380087-86-4. Molecular Formula: C20H15Cl2N3O2. Formula Weight: 400.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml. lambdamax: 256 nm. SMILES: NC(C[C@@H]1N=C(C2=CC=C(Cl)C=C2)C3=C(C=CC(Cl)=C3)C4=C1ON=C4C)=O. InChi Code: InChI=1S/C20H15Cl2N3O2/c1-10-18-14-7-6-13(22)8-15(14)19(11-2-4-12(21)5-3-11)24-16(9-17(23)26)20(18)27-25-10/h2-8,16H,9H2,1H3,(H2,23,26)/t16-/m0/s1. InChi Key: RKYPLOAYXFDLOF-INIZCTEOSA-N.