Clothianidin

Description: Clothianidin (TI 435), an insecticide, acts as an agonist of acetylcholine to stimulate nAChR, thereby activating post-synaptic acetylcholine receptors but not inhibiting AChE. Target: AChR. Smiles: C\N=C(\NCc1cnc(Cl)s1)N[N+]([O-])=O. References: Montiel-León JM, Munoz G, Vo Duy S, Do DT, Vaudreuil MA, Goeury K, Guillemette F, Amyot M, Sauvé S. Widespread occurrence and spatial distribution of glyphosate, atrazine, and neonicotinoids pesticides in the St. Lawrence and tributary rivers. Environ Pollut. 2019 Apr 2,250:29-39.