Clavulanate (potassium salt)

Clavulanate is a beta-lactamase inhibitor that is effective against Ambler class A beta-lactamases (IC50 values range from 12 to 60 nM). While it is not an effective antibiotic by itself, clavulanate is commonly used with other antibiotics that would be inactivated by beta-lactamases secreted by bacteria. It is often combined with amoxicillin (Cay-19188) and other penicillin-based antibiotics.Formal Name: (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, monopotassium salt. CAS Number: 61177-45-5. Synonyms: BRL 14151K. Molecular Formula: C8H8NO5 . K. Formula Weight: 237.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/mL. lambdamax: 218, 312, 355 nm. SMILES: O=C1C[C@]2([H])N1[C@@H](C([O-])=O)/C(O2)=C/CO.[K+]. InChi Code: InChI=1S/C8H9NO5.K/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4,/h1,6-7,10H,2-3H2,(H,12,13),/q,+1/p-1/b4-1-,/t6-,7-,/m1./s1. InChi Key: ABVRVIZBZKUTMK-JSYANWSFSA-M.