cis-10-hydroxy Nortriptyline

cis-10-hydroxy Nortriptyline is an active metabolite of the tricyclic antidepressants amitriptyline (Cay-15881) and nortriptyline (Cay-15904). It is formed from amitriptyline and nortriptyline by the cytochrome P450 (CYP) isoform CYP2D6. cis-10-hydroxy Nortriptyline inhibits norepinephrine reuptake in rat cortical slices (EC50 = 160 nM).Formal Name: (5Z)-10,11-dihydro-5-[3-(methylamino)propylidene]-5H-dibenzo[a,d]cyclohepten-10-ol. CAS Number: 47132-19-4. Synonyms: 10(Z)-hydroxy Nortriptyline. Molecular Formula: C19H21NO. Formula Weight: 279.4. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMF:PBS (pH 7.2) (1:1): 0.50 mg/ml, DMSO: 10 mg/ml, Ethanol: 5 mg/ml. SMILES: CNCC/C=C1C2=CC=CC=C2C(CC3=CC=CC=C3\1)O. InChi Code: InChI=1S/C19H21NO/c1-20-12-6-11-16-15-8-3-2-7-14(15)13-19(21)18-10-5-4-9-17(16)18/h2-5,7-11,19-21H,6,12-13H2,1H3/b16-11-. InChi Key: VAGXZGJKNUNLHK-WJDWOHSUSA-N.