Cefoperazone (sodium salt)

Cefoperazone is a cephalosporin antibiotic that is active in vitro against most Gram-positive and Gram-negative bacteria, including beta-lactamase strains (3-4 µg/ml inhibits 90% of S. aureus growth). It has been studied in the treatment of upper and lower respiratory tract infections, urinary tract infections, gynecological infections, skin infections, as well as bacteremia.Formal Name: (6R,7R)-7-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monosodium salt. CAS Number: 62893-20-3. Synonyms: Cefoneg, Cefosint, CP 52,640-2, Perocef. Molecular Formula: C25H26N9O8S2 . Na. Formula Weight: 667.7. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 3 mg/ml. lambdamax: 229, 268 nm. SMILES: CCN(CCN(C(N[C@H](C1=CC=C(O)C=C1)C(N[C@@H]2C(N3[C@]2([H])SCC(CSC4=NN=NN4C)=C3C([O-])=O)=O)=O)=O)C5=O)C5=O.[Na+]. InChi Code: InChI=1S/C25H27N9O8S2.Na/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2,/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41),/q,+1/p-1/t15-,16-,22-,/. InChi Key: NCFTXMQPRQZFMZ-WERGMSTESA-M.