Cefmetazole

Cefmetazole is a cephamycin antibiotic. It is active against E. coli, P. mirabilis, H. influenzae, N. gonorrhoeae, S. pneumoniae, and S. pyogenes (MIC50s = 0.25-2 µg/ml). Cefmetazole (20 and 40 mg/kg per day) decreases the lesion size and the number of ulcerative lesions in a rabbit model of active syphilis.Formal Name: (6R,7S)-7-[[2-[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. CAS Number: 56796-20-4. Molecular Formula: C15H17N7O5S3. Formula Weight: 471.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: 20mg/mL, DMSO: 20mg/mL, DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL. lambdamax: 277 nm. SMILES: O=C(O)C1=C(CSC2=NN=NN2C)CS[C@@]([C@]3(OC)NC(CSCC#N)=O)([H])N1C3=O. InChi Code: InChI=1S/C15H17N7O5S3/c1-21-14(18-19-20-21)30-6-8-5-29-13-15(27-2,17-9(23)7-28-4-3-16)12(26)22(13)10(8)11(24)25/h13H,4-7H2,1-2H3,(H,17,23)(H,24,25)/t13-,15+/m1/s1. InChi Key: SNBUBQHDYVFSQF-HIFRSBDPSA-N.