CAY10554

Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising therapeutic targets for cancer and neurodegenerative diseases. CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.Formal Name: N-[5-(1-methylethyl)2-thiazolyl]-benzeneacetamide. CAS Number: 267654-00-2. Synonyms: BML-259. Molecular Formula: C14H16N2OS. Formula Weight: 260.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2)(1:2): 0.3 mg/ml, Ethanol: 0.25 mg/ml. lambdamax: 275 nm. SMILES: O=C(Cc1ccccc1)Nc1ncc(s1)C(C)C. InChi Code: InChI=1S/C14H16N2OS/c1-10(2)12-9-15-14(18-12)16-13(17)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,15,16,17). InChi Key: IGRZXNLKVUEFDM-UHFFFAOYSA-N.