Carviolin

Carviolin is an anthraquinone fungal metabolite that has been found in Z. longicaudata with immunosuppressive and antitrypanosomal activities. It inhibits LPS- or concanavalin A-induced proliferation of mouse splenocytes (IC50s = 4 and 4.5 µg/ml, respectively). Carviolin is active against T. b. brucei (MIC = 41.66 µM).Formal Name: 1,3-dihydroxy-6-(hydroxymethyl)-8-methoxy-9,10-anthracenedione. CAS Number: 478-35-3. Molecular Formula: C16H12O6. Formula Weight: 300.3. Purity: >70%. Formulation: (Request formulation change), A solid. Solubility: Dichloromethane: soluble, DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: O=C1C2=C(C=C(CO)C=C2OC)C(C3=CC(O)=CC(O)=C31)=O. InChi Code: InChI=1S/C16H12O6/c1-22-12-3-7(6-17)2-9-14(12)16(21)13-10(15(9)20)4-8(18)5-11(13)19/h2-5,17-19H,6H2,1H3. InChi Key: XNMZBRJAWRIJII-UHFFFAOYSA-N. Origin: Bacterium/Penicillium sp..