Carbimazole

Carbimazole is a prodrug form of the thyroid hormone synthesis inhibitor methimazole (Cay-23718). Carbimazole (15 mg/animal) reduces total thyroxine concentration, thyroid enlargement, polyphagia, anorexia, and alopecia in a cat model of hyperthyroidism.Formal Name: 2,3-dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid, ethyl ester. CAS Number: 22232-54-8. Molecular Formula: C7H10N2O2S. Formula Weight: 186.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1mg/mL, DMSO: 1mg/mL, Ethanol: 1mg/mL, Ethanol:PBS (pH 7.2) (1:5): 0.10mg/mL. lambdamax: 223, 301, 352, 371 nm. SMILES: CN(C=CN1C(OCC)=O)C1=S. InChi Code: InChI=1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3. InChi Key: CFOYWRHIYXMDOT-UHFFFAOYSA-N.