Carbazochrome

Carbazochrome is a hemostatic agent. In vivo, carbazochrome (0.1 mg/kg) reduces blood loss by 45% in a mouse model of traumatic hemorrhage. Topical administration of carbazochrome induces blood coagulation at back wound sites in mice.Formal Name: 2-(1,2,3,6-tetrahydro-3-hydroxy-1-methyl-6-oxo-5H-indol-5-ylidene)-hydrazinecarboxamide. CAS Number: 69-81-8. Synonyms: Adrenochrome Monosemicarbazone, Adrenochrome Semicarbazone, NSC 73742. Molecular Formula: C10H12N4O3. Formula Weight: 236.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/ml, DMSO: 1 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml. lambdamax: 358 nm. SMILES: O=C(NN=C1C=C2C(N(CC2O)C)=CC1=O)N. InChi Code: InChI=1S/C10H12N4O3/c1-14-4-9(16)5-2-6(12-13-10(11)17)8(15)3-7(5)14/h2-3,9,16H,4H2,1H3,(H3,11,13,17). InChi Key: XSXCZNVKFKNLPR-UHFFFAOYSA-N.