Busulfan-d8

Busulfan-d8 is intended for use as an internal standard for the quantification of busulfan (Cay-14843) by GC- or LC-MS. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. It forms both intra- and interstrand crosslinks on DNA. In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels or humoral antibody responses.Formal Name: 1,4-butane-1,1,2,2,3,3,4,4-d8-diol, dimethanesulfonate. CAS Number: 116653-28-2. Synonyms: Busulphan-d8, Mielosan-d8, Milecitan-d8, Myeloleukon-d8, Mylecytan-d8, Myleran-d8. Molecular Formula: C6H6D8O6S2. Formula Weight: 254.3. Purity: >99% deuterated forms (d1-d8). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 16.7 mg/ml, DMSO: 16.7 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 256 nm. SMILES: CS(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])OS(C)(=O)=O)(=O)=O. InChi Code: InChI=1S/C6H14O6S2/c1-13(7,8)11-5-3-4-6-12-14(2,9)10/h3-6H2,1-2H3/i3D2,4D2,5D2,6D2. InChi Key: COVZYZSDYWQREU-SQUIKQQTSA-N.