Biotin-DEVD-CHO (trifluoroacetate salt)

Biotin-DEVD-CHO is a biotin-conjugated form of the caspase-3 and -7 inhibitor Ac-DEVD-CHO (Cay-10017). It has been used for affinity purification of active caspase-3, -6, -7, and -8. Biotin-DEVD-CHO has also been used for detection of active caspase-3 in tissue samples and permeabilized cells using affinity labeling with streptavidin conjugates.Formal Name: N-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-L-alpha-aspartyl-L-alpha-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-valinamide, trifluoroacetate salt. Synonyms: Biotin-Asp-Glu-Val-Asp-CHO. Molecular Formula: C28H42N6O12S . XCF3COOH. Formula Weight: 686.7. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Formic Acid: 1 mg/ml. SMILES: OC(CC[C@H](NC([C@H](CC(O)=O)NC(CCCC[C@@H]1[C@@](NC(N2)=O)([H])[C@@]2([H])CS1)=O)=O)C(N[C@@H](C(C)C)C(N[C@H](C=O)CC(O)=O)=O)=O)=O.FC(F)(C(O)=O)F. InChi Code: InChI=1S/C28H42N6O12S.C2HF3O2/c1-13(2)23(27(45)29-14(11-35)9-21(39)40)33-25(43)15(7-8-20(37)38)31-26(44)16(10-22(41)42)30-19(36)6-4-3-5-18-24-17(12-47-18)32-28(46)34-24,3-2(4,5)1(6)7/h11,13-18,23-24H,3-10,12H2,1-2H3,(H,29,45)(H,30,36)(H,31,44)(H,33,43)(H,37,38)(H,39,40)(H,41,42)(H2,32,34,46),(H,6,7)/t14-,15-,16-,17+,18+,23-,24+,/m0./s1. InChi Key: KNYCBYIWLOLJSR-XOFSVAJBSA-N.