BI-01383298

BI-01383298 is an inhibitor of the sodium-coupled citrate transporter (NaCT, IC50 = ~100 nM). It irreversibly inhibits sodium-dependent citrate uptake, but not nicotinate, arginine, glutamine, tryptophan, or lactate uptake, in HepG2 cells when used at concentrations ranging from 0.01 to 1 µM.Formal Name: 1-[(3,5-dichlorophenyl)sulfonyl]-N-[(4-fluorophenyl)methyl]-4-piperidinecarboxamide. CAS Number: 2227549-00-8. Molecular Formula: C19H19Cl2FN2O3S. Formula Weight: 445.3. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 5 mg/ml. SMILES: ClC1=CC(Cl)=CC(S(N2CCC(C(NCC3=CC=C(F)C=C3)=O)CC2)(=O)=O)=C1. InChi Code: InChI=1S/C19H19Cl2FN2O3S/c20-15-9-16(21)11-18(10-15)28(26,27)24-7-5-14(6-8-24)19(25)23-12-13-1-3-17(22)4-2-13/h1-4,9-11,14H,5-8,12H2,(H,23,25). InChi Key: VUOYAALVGSMUHC-UHFFFAOYSA-N.