beta-Glucuronidase-IN-1

Description: beta-Glucuronidase-IN-1 is an E. coli beta-glucuronidase (beta-glucuronidase) inhibitor with a potent, selective, non-competitive, and orally active IC50 and Ki value of 283 nM and 164 nM, respectively, against E. coli beta-glucuronidase. Target: Antibacterial. Smiles: CCOc1ccc(NC(=S)N(CCO)Cc2cc3cc(C)cc(C)c3[nH]c2=O)cc1. References: Wallace BD, et al. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.Science. 2010 Nov 5,330(6005):831-5.