beta-Cyclodextrin

Synthetic. Chemical. CAS: 7585-39-9. Formula: C42H70O35. MW: 1134.98. Synthetic. Most commonly used as a complexing agent in food, pharmaceutical, drug delivery and chemical industries, as well as agriculture and environmental engineering. Forms complexes with hydrophobic compounds to enhance solubility and bioavailability (Drug Delivery System DDS). Commonly used to produce HPLC columns allowing chiral enantiomers separation. Used to remove large hydrophobic molecules like cholesterol. Reported to be useful for the selective precipitation of enantiomeric, positional or structural isomers. Cyclodextrins are cyclic oligosaccharides consisting of 6, 7, or 8 glucopyranose units with hydrophobic interiors, usually referred to as alpha-, beta- or gamma-cyclodextrins, respectively. Lipophilic drugs of a size compatible with the hydrophobic core of a cyclodextrin can form complexes, resulting in increased aqueous solubility of the drugs. Cyclodextrins are non-toxic in many species and do not denature proteins or interfere with enzymatic reactions.