BD 1008 dihydrobromide

Description: BD 1008 dihydrobromide is a selective antagonist of the sigma 1 (sigma1) receptor (Ki = 2 nM). BD 1008 dihydrobromide have high affinity for sigma1 receptors, moderate affinity for sigma2 receptors. Target: Sigma receptor. Smiles: [H]Br.[H]Br.CN(CCC1=CC=C(Cl)C(Cl)=C1)CCN2CCCC2. References: Garcés-Ramírez L, et al. Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis. Biol Psychiatry. 2011 Feb 1,69(3):208-17.