B-HT 920 (hydrochloride)

B-HT 920 is a potent agonist of dopamine 2 (D2) receptors (Ki = 5.8 nM) that shows selectivity for D2 over D3 and D4 receptors. It has neuroprotective and regenerative effects in animal models of Parkinson's disease. B-HT 920 is also an agonist of alpha2-adrenergic receptors and an antagonist of serotonin-3 (5-HT3, Ki = 0.35 µM) receptors.Formal Name: 5,6,7,8-tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d]azepin-2-amine, dihydrochloride. CAS Number: 36085-73-1. Molecular Formula: C10H15N3S . 2HCl. Formula Weight: 282.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 225, 263 nm. SMILES: NC(S1)=NC2=C1CCN(CC=C)CC2.Cl.Cl. InChi Code: InChI=1S/C10H15N3S.2ClH/c1-2-5-13-6-3-8-9(4-7-13)14-10(11)12-8,,/h2H,1,3-7H2,(H2,11,12),2*1H. InChi Key: DPQAXNSOFFYKDS-UHFFFAOYSA-N.