AZD6703 free base

Description: AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase 14 (MAPK14). Target: Others. Smiles: O=C1C=2C(N=CN1C3=CC(C(NC4CC4)=O)=CC=C3C)=CC=C(C2)N5CCN(C)CC5. References: Brown DS, Cumming JG, Bethel P, Finlayson J, Gerhardt S, Nash I, Pauptit RA, Pike KG, Reid A, Snelson W, Swallow S, Thompson C. The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]ben zamide (AZD6703), a clinical p38alpha MAP kinase inhibitor for the treatment of inflammatory diseases. Bioorg Med Chem Lett. 2012 Jun 15,22(12):3879-83. doi: 10.1016/j.bmcl.2012.04.116. PubMed PMID: 22608965.