Asoxime dichloride

Description: Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, alpha7 nAChR. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system. Asoxime dichloride involves in modulating immunity response. Target: AChR. Smiles: ON=CC1=CC=CC=[N+]1COC[N+]2=CC=C(C(N)=O)C=C2.[Cl-].[Cl-]. References: Pohanka M, et al. HI-6 modulates immunization efficacy in a BALB/c mouse model.Environ Toxicol Pharmacol. 2013 Nov,36(3):801-6.