ARN19874

Description: ARN19874 is a selective, reversible uncompetitive inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) activity, with an IC50 of approximately 34 µM[1]. Target: Others. Smiles: O=C1C=2C(=CC=C(S(NC3=CC=C(C=C3)C=4C=CN=CC4)(=O)=O)C2)NC(=O)N1. References: Castellani B, et al. Synthesis and characterization of the first inhibitor of N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD). Chem Commun (Camb). 2017 Nov 28,53(95):12814-12817.