AMP-Deoxynojirimycin

Description: AMP-Deoxynojirimycin (AMP-DNM) is a potent inhibitor of ceramide glucosyltransferase and GCase 2, as well as GlcCer biosynthesis, and is utilized in the study of Parkinson's disease and diabetes. Target: Glucosidase, Transferase. Smiles: C(OCCCCCN1[C@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C1)C23CC4CC(C2)CC(C3)C4. References: Bae EJ, et al. Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and alpha-synuclein aggregation. Exp Mol Med. 2015 Mar 27,47(3):e153.