alpha-Galactosylceramide

Description: alpha-Galactosylceramide (KRN7000) is a synthetic glycolipid with antitumorial and immunostimulatory and is a very potent NKT cell agonist and binds effectively to CD1d. The complex of alpha-Galactosylceramide and CD1d can bind to the T cell antigen receptor of NKT cells. Target: Others. Smiles: CCCCCCCCCC CCCCCCCCCC CCCCCC(=O)N[C@@H](CO[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O)[C@H](O)[C@H](O)CCCCCCCCCCCCCC. References: Godfrey DI, et al. Going both ways: immune regulation via CD1d-dependent NKT cells. J Clin Invest. 2004 Nov,114(10):1379-88.