alpha,beta-Methylene ATP trisodium

Description: alpha,beta-Methylene ATP trisodium, a phosphonate analog of ATP, is a selective P2X agonist that induces enhanced contraction of UBSM. alpha,beta-Methylene ATP trisodium inhibits P2X1 and P2X3, but is inactive against P2X2, 4 and 7. Target: P2X Receptor. Smiles: O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(CP(OP([O-])(O)=O)([O-])=O)([O-])=O)N2C3=NC=NC(N)=C3N=C2.[Na+].[Na+].[Na+]. References: Arribas-Blázquez M, et al. Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain. Int J Mol Sci. 2019 Jan 3,20(1).