Alovudine

Description: Alovudine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis. Alovudine is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and is a better biomarker in pancreatic cancer. Target: Antiviral. Smiles: Cc1cn([C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]c1=O. References: Ghosn, J., Quinson, A., Sabo, N., Cotte, L., Piketty, C., & Dorléacq, N. et al. (2007). Antiviral activity of low-dose alovudine in antiretroviral-experienced patients: results from a 4-week randomized, double-blind, placebo-controlled dose-ranging trial. HIV Medicine, 8(3), 142-147. doi: 10.1111/j.1468-1293.2007.00444.x