all-trans-5,6-epoxy Retinoic Acid

all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR, EC50s = 77, 35, and 4 nM for RARalpha, RARbeta, and RARgamma, respectively). 5,6-epoxy RA (1 µM) also induces growth arrest of MCF-7 and NB4 cells in vitro.{34780, 34781} It is a natural metabolite of all-trans retinoic acid (Cay-11017), which is a metabolite of vitamin A.Formal Name: 5,6-epoxy-5,6-dihydro-retinoic acid. CAS Number: 13100-69-1. Synonyms: 5,6-epoxy atRA, 5,6-epoxy RA. Molecular Formula: C20H28O3. Formula Weight: 316.4. Purity: >96%. Formulation: (Request formulation change), A solid. Solubility: Chloroform: Soluble, Methanol: Soluble. SMILES: CC1(O2)C2(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)C(C)(C)CCC1. InChi Code: InChI=1S/C20H28O3/c1-15(8-6-9-16(2)14-17(21)22)10-13-20-18(3,4)11-7-12-19(20,5)23-20/h6,8-10,13-14H,7,11-12H2,1-5H3,(H,21,22)/b9-6+,13-10+,15-8+,16-14+. InChi Key: KEEHJLBAOLGBJZ-WEDZBJJJSA-N.