Akt-I-1

Akt-I-1 is an inhibitor of Akt1 (IC50 = 4.6 µM). It is selective for Akt1 over Akt2, Akt3, and serum/glucocorticoid-regulated kinase (SGK, IC50s = >250 µM for all).Formal Name: N3-(7-cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N1,N1,2,2-tetramethyl-1,3-propanediamine. CAS Number: 473382-39-7. Synonyms: Akt-IN-1. Molecular Formula: C22H30N6. Formula Weight: 378.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Ethanol: Sparingly Soluble: 1-10 mg/ml. SMILES: CN(CC(C)(CNC1=NN2C(C=C1C3CCC3)=NN=C2C4=CC=CC=C4)C)C. InChi Code: InChI=1S/C22H30N6/c1-22(2,15-27(3)4)14-23-20-18(16-11-8-12-16)13-19-24-25-21(28(19)26-20)17-9-6-5-7-10-17/h5-7,9-10,13,16H,8,11-12,14-15H2,1-4H3,(H,23,26). InChi Key: FKCXKEHHZXEWGP-UHFFFAOYSA-N.