AGN-191129

Description: AGN-191129, also known as Prostaglandin F2alpha alcohol methyl ether (PGF2alpha-OMe), is an analog of PGF2alpha in which the C-1 carboxyl group has been replaced by an O-methyl ether. The compound is reported to retain ocular hypotensive properties, but the receptors which mediate this activity have not been clearly documented. Target: Others. Smiles: C(/C=C\CCCCOC)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)C[C@@H]1O. References: Woodward, D.F., and Chan, M.F. Preparation of PGF-1 alcohols as ocular hypotensives 38204, 1-12 (1993).