ADR-925

Description: ADR-925 (ICRF 198), an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from adriamycin-induced injury. Target: Endogenous Metabolite. Smiles: N([C@H](CN(CC(N)=O)CC(O)=O)C)(CC(N)=O)CC(O)=O. References: Jirkovský E, et al. Pharmacokinetics of the Cardioprotective Drug Dexrazoxane and Its Active Metabolite ADR-925 with Focus on Cardiomyocytes and the Heart. J Pharmacol Exp Ther. 2018,364(3):433-446.