Adenosine 5'-(gamma-thio)-triphosphate (lithium salt)

Adenosine 5'-(gamma-thio)-triphosphate (lithium salt) is a stable analog of ATP that acts as a potent agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, has been implemented as a reagent in the synthesis of DNA N-acetylglucosamine analogs, and can serve as a substrate for the RNA-stimulated nucleotide hydrolysis and RNA unwinding activities of eukaryotic initiation factor-4A.Formal Name: P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen diphosphate), tetralithium salt. CAS Number: 93839-89-5. Synonyms: ATPgammaS. Molecular Formula: C10H12N5O12P3S . 4Li. Formula Weight: 547.0. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 259 nm. SMILES: O=P(OP(OP([O-])([O-])=S)([O-])=O)([O-])OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1.[Li+].[Li+].[Li+].[Li+]. InChi Code: InChI=1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31,,,,/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31),,,,/q,4*+1/p-4/t4-,6-,7-,10-,,,,/m1..../s1. InChi Key: DWQFDOIBOYDYKH-KWIZKVQNSA-J.