Abediterol

Description: Abediterol (LAS100977) is a new potent, long-acting inhaled beta (2) -adrenergic receptor agonist being developed for the treatment of asthma and chronic obstructive pulmonary disease. Target: Others. Smiles: [C@@H](CNCCCCCCOCC(F)(F)C1=CC=CC=C1)(O)C2=C3C(=C(O)C=C2)NC(=O)C=C3. References: Aparici M, Gavaldà A, Ramos I, Carcasona C, Otal R, Fernández-Blanco JA, Montero JL, García VM, López R, De Alba J, Doe C, Puig C, Vilella D, Miralpeix M. In vitro and in vivo preclinical profile of abediterol (LAS100977), an inhaled long-acting beta2-adrenoceptor agonist, compared with indacaterol, olodaterol and vilanterol. Eur J Pharmacol. 2016 Jan 5,770:61-9. doi: 10.1016/j.ejphar.2015.11.053. Epub 2015 Dec 4. PubMed PMID: 26656755.