A6770

A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase. It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50 = 6 (EC50 = <100 µM).Formal Name: 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]-ethanone. CAS Number: 1331754-16-5. Molecular Formula: C6H8N2O2. Formula Weight: 140.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 280 nm. SMILES: OCC1=CN=C(C(C)=O)N1. InChi Code: InChI=1S/C6H8N2O2/c1-4(10)6-7-2-5(3-9)8-6/h2,9H,3H2,1H3,(H,7,8). InChi Key: JXDVIQLWMKAZBS-UHFFFAOYSA-N.