A 784168

Description: A-784168, a potent and orally active inhibitor of vanilloid receptor type 1 (TRPV1), acts on a ligand-gated nonselective cation channel pivotal in integrating pain stimuli including endogenous lipids, capsaicin, heat, and low pH. It demonstrates commendable central nervous system (CNS) penetration upon oral administration [1]. Target: Others. Smiles: C(F)(F)(F)C1=C(N=CC=C1)N2CCC(C(NC3=CC=C(S(C(F)(F)F)(=O)=O)C=C3)=O)=CC2