8-Azaadenosine

Description: 8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells. Target: Adenosine deaminase. Smiles: Nc1ncnc2n(nnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O. References: Bennett L L , Allan P W . Metabolism and Metabolic Effects of 8-Azainosine and 8-Azaadenosine[J]. Cancer Research, 1976, 36(11 Pt 1):3917.