7-Dehydrocholesterol

Description: 7-Dehydrocholesterol (Provitamin D3) down-regulates cholesterol biosynthesis in cultured Smith-Lemi-Opitz syndrome skin fibroblasts. Target: Endogenous Metabolite. Smiles: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C. References: Lehmann B , Genehr T , Knuschke P , et al. UVB-Induced Conversion of 7-Dehydrocholesterol to 1alpha,25-Dihydroxyvitamin D3 in an In Vitro Human Skin Equivalent Model[J]. Journal of Investigative Dermatology, 2001, 117(5):1179.