5-Aminolevulinic Acid (hydrochloride)

5-Aminolevulinic acid (5-ALA) is a precursor in the biosynthesis of porphyrins, including heme. The conversion of 5-ALA to protoporphyrins within tissues produces a photosensitive target that produces reactive oxygen species upon exposure to light. In this way, it is used in photodynamic therapy for a range of dermatological conditions, cancers, and other diseases. Also, oral administration of 5-ALA leads to the preferential accumulation of the fluorescent molecule protoporphyrin IX within certain types of cancer cells. This allows fluorescence-based identification of tumor tissue for accurate resection of diseased tissue.Formal Name: 5-amino-4-oxo-pentanoic acid, monohydrochloride. CAS Number: 5451-09-2. Synonyms: 5-ALA, delta-Aminolevulinic Acid. Molecular Formula: C5H9NO3 . HCl. Formula Weight: 167.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 265 nm. SMILES: NCC(CCC(O)=O)=O.Cl. InChi Code: InChI=1S/C5H9NO3.ClH/c6-3-4(7)1-2-5(8)9,/h1-3,6H2,(H,8,9),1H. InChi Key: ZLHFONARZHCSET-UHFFFAOYSA-N.