4',7-Di-O-methylnaringenin

4',7-Di-O-methylnaringenin is a flavonoid aglycone that has been found in Vitex quinata and has potassium channel inhibitory and anticancer activities. It inhibits the voltage-gated potassium channel subtype Kv1.3 in a patch-clamp assay when used at a concentration of 30 µM. 4',7-Di-O-methylnaringenin is cytotoxic to human LNCaP prostate, Lu1 lung, and MCF-7 breast cancer cells (EC50s = 6.7, 4.7, and 1.1 µM, respectively).Formal Name: 2S,3-dihydro-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one. CAS Number: 29424-96-2. Synonyms: Naringenin 4',7-dimethyl ether. Molecular Formula: C17H16O5. Formula Weight: 300.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 215, 227, 287 nm. SMILES: OC1=C2C(O[C@@H](CC2=O)C3=CC=C(OC)C=C3)=CC(OC)=C1. InChi Code: InChI=1S/C17H16O5/c1-20-11-5-3-10(4-6-11)15-9-14(19)17-13(18)7-12(21-2)8-16(17)22-15/h3-8,15,18H,9H2,1-2H3/t15-/m0/s1. InChi Key: CKEXCBVNKRHAMX-HNNXBMFYSA-N. Origin: Plant/Aglaia odorata.