4,5,6,7-Tetrabromobenzimidazole

Artikelnummer	Größe	Datenblatt	Manual	SDB	Lieferzeit	Menge	Preis
Cay18886-10	10 mg		-		6 - 10 Werktage*		106,00 €
Cay18886-50	50 mg		-		6 - 10 Werktage*		423,00 €

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Casein kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction... mehr

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Produktinformationen "4,5,6,7-Tetrabromobenzimidazole"

Casein kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors. 4,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of CK2 with Ki values ranging from 0.5-1 µM in rat liver, S. cerevisiae, C. tropicalis, and N. crassa. It is inactive against PKA and PKC and a relatively weak inhibitor of CK1 (Ki = 54.4-64.2 µM).Formal Name: 4,5,6,7-tetrabromo-1H-benzimidazole. CAS Number: 577779-57-8. Synonyms: Casein Kinase II Inhibitor XII, TBBz. Molecular Formula: C7H2Br4N2. Formula Weight: 433.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: Soluble, Ethanol: Soluble. SMILES: BrC1=C2C(N=CN2)=C(Br)C(Br)=C1Br. InChi Code: InChI=1S/C7H2Br4N2/c8-2-3(9)5(11)7-6(4(2)10)12-1-13-7/h1H,(H,12,13). InChi Key: LOEIRDBRYBHAJB-UHFFFAOYSA-N.

Schlagworte:	Casein Kinase II Inhibitor XII, TBBz, 4,5,6,7-tetrabromo-1H-benzimidazole
Hersteller:	Cayman Chemical
Hersteller-Nr:	18886

Eigenschaften

Anwendung:	CK2 inhibitor
MW:	433.7 D
Formel:	C7H2Br4N2
Reinheit:	>98%
Format:	Crystalline Solid

Datenbank Information

CAS :	577779-57-8\| Passende Produkte
KEGG ID :	K03097 \| Passende Produkte

Handhabung & Sicherheit

Lagerung:	-20°C
Versand:	+20°C (International: -20°C)
Signalwort:	Danger
GHS-Piktogramme:
H-Sätze:	H301, H319
P-Sätze:	P264, P270, P280, P301+310, P305+351+338, P321, P330, P337+313, P405, P501