3-Bromotyrosine (trifluoroacetate salt)

3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response. It has been used as a marker of eosinophil peroxidase-induced protein oxidation in vitro and in vivo. In addition to its production in eosinophils, 3-bromotyrosine is found at 5-fold higher levels in peritoneal exudate from mice infected with K. pneumoniae compared with uninfected animals, suggesting neutrophils release higher levels of oxidized products during inflammation. In a human study, 3-bromotyrosine was increased 10-fold in allergen-challenged lung samples from subjects with allergen-induced asthma.Formal Name: 3-bromo-L-tyrosine, monotrifluoroacetate salt. CAS Number: 2320428-62-2. Synonyms: 3-bromo-Tyr. Molecular Formula: C9H10BrNO3 . CF3COOH. Formula Weight: 374.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: BrC1=C(O)C=CC(C[C@H](N)C(O)=O)=C1.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C9H10BrNO3.C2HF3O2/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14,3-2(4,5)1(6)7/h1-3,7,12H,4,11H2,(H,13,14),(H,6,7)/t7-,/m0./s1. InChi Key: ZTELCZMTUMDSGB-FJXQXJEOSA-N.