20-hydroxy Ecdysone

20-hydroxy Ecdysone is an ecdysteroid hormone produced in arthropod species that induces developmental changes associated with ecdysis and the completion of metamorphosis. It is also produced in plants as a defensive strategy to disrupt the development of insect pests. In target tissues, 20-hydroxy ecdysone binds to the nuclear hormone receptor, ecdysone receptor, initiating a signaling cascade that results in cell cycle arrest. Ecdysteroids such as this compound have been employed as tools in inducible gene regulation systems controlled by reporter cells transfected with the ecdysone receptor.Formal Name: (5beta)-2beta,3beta,14,20,22R,25-hexahydroxy-cholest-7-en-6-one. CAS Number: 5289-74-7. Synonyms: Ecdysterone, Isoinokosterone. Molecular Formula: C27H44O7. Formula Weight: 480.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 25 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 243 nm. SMILES: O=C1[C@]2([H])C[C@@H](O)[C@@H](O)C[C@]2(C)[C@]3([H])C([C@@](CC[C@]4([H])[C@]([C@H](O)CCC(C)(O)C)(O)C)(O)[C@]4(C)CC3)=C1. InChi Code: InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1. InChi Key: NKDFYOWSKOHCCO-YPVLXUMRSA-N.