2-oxo Clopidogrel

2-oxo Clopidogrel is an intermediate metabolite of (±)-clopidogrel (Cay-13657), which consists of R-(-)-clopidogrel and the active isomer S-(+)-clopidogrel (Cay-21002). (S)-(+)-clopidogrel is metabolized by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 into 2-oxo (S)-(+)-clopidogrel, which is then further metabolized into the active metabolite of clopidogrel by CYP2B6, CYP2C9, CYP2C19, and CYP3A4.Formal Name: alpha-(2-chlorophenyl)-2,6,7,7a-tetrahydro-2-oxo-thieno[3,2-c]pyridine-5(4H)-acetic acid, methyl ester. CAS Number: 109904-27-0. Molecular Formula: C16H16ClNO3S. Formula Weight: 337.8. Purity: >98% (mixture of diastereomers). Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMF:PBS (pH 7.2) (1:20): 0.04 mg/ml, DMSO: 20 mg/ml, Ethanol: 5 mg/ml. lambdamax: 218 nm. SMILES: ClC1=CC=CC=C1C(C(OC)=O)N2CCC(S3)C(C2)=CC3=O. InChi Code: InChI=1S/C16H16ClNO3S/c1-21-16(20)15(11-4-2-3-5-12(11)17)18-7-6-13-10(9-18)8-14(19)22-13/h2-5,8,13,15H,6-7,9H2,1H3. InChi Key: JBSAZVIMJUOBNB-UHFFFAOYSA-N.