2,5-Anhydro-D-mannitol

2,5-Anhydro-D-mannitol is an antimetabolic fructose analogue that increases food intake in rats at doses of 50-800 mg/kg by inhibiting gluconeogenesis and glycogenolysis in the liver.. It is phosphorylated in the liver, which decreases available ATP and signals eating behavior in rats through a vagal nerve mechanism.Formal Name: (2R,3S,4S,5R)-2,5-bis(hydroxymethyl)tetrahydrofuran-3,4-diol. CAS Number: 41107-82-8. Synonyms: 2,5-AHM, NSC 129241. Molecular Formula: C6H12O5. Formula Weight: 164.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 30 mg/ml, Ethanol: 5 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1. InChi Code: InChI=1S/C6H12O5/c7-1-3-5(9)6(10)4(2-8)11-3/h3-10H,1-2H2/t3-,4-,5-,6-/m1/s1. InChi Key: MCHWWJLLPNDHGL-KVTDHHQDSA-N.