2,3-dinor Thromboxane B2

Description: Thromboxane B2 (TXB2) is a compound significantly released from aggregating platelets and undergoes metabolic transformation during circulation into 11-dehydro TXB2 and 2,3-dinor TXB2. The latter, 2,3-dinor TXB2, serves as a prevalent urinary metabolite of TXB2 and acts as an indicator for in vivo TXA2 synthesis. Studies have shown that in healthy male volunteers, the median excretion rate of 2,3-dinor TXB2 is measured at 10.3 ng/hour, equivalent to 138 pg/mg of creatinine. Target: Others. Smiles: C(/C=C\CC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)O[C@@H](O)C[C@@H]1O