11-Dehydrocorticosterone

A steroid extracted from the adrenal cortex. 11-Dehydrocorticosterone is a precursor to corticosterone converted by 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) which plays a role in glucocorticoid-induced insulin resistance. Alternate Name: 4-Pregnen-21-ol-3, 11, 20-trione, 11-Oxo-11-deoxycorticosterone, 11-Oxocorticosterone,, 17-(1-keto-2-Hydroxyethyl)-Delta4-androsten-3,11-dione, 4-Pregnen-21-ol-3,11,20-trione,, 11-Dehydro-corticosterone, Dehydrocorticosterone, Kendall's compound A,, NSC-9702, Delta4-Pregnen-21-ol-3,11,20-trione, Delta4-Pregnene-21-ol-3,11,20-trione, CAS Number: 72-23-1, Molecular Formula: C21H28O4, Molecular Weight: 344.44, Appearance: Supplied as an off-white solid. Purity: >98% (TLC), Melting Point: 175.8-182.1°C, Specific Rotation (Chloroform): +268.0°, Identification (IR): Conforms to reference, TLC Conditions: Toluene: Acetone, 20:5, Visualized with UV and p/TSA iodine, Single spot, Rf=0.21, Solubility: Soluble in most organic solvents. Insoluble in water. Chloroform (Slightly), Dioxane (Slightly), Methanol (Slightly), Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt.. For maximum recovery of product, centrifuge the original vial prior to removing the cap.