1-Methyladenosine

1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.Formal Name: 1-methyl-adenosine. CAS Number: 15763-06-1. Synonyms: 1-methyl Ado, NSC 92165. Molecular Formula: C11H15N5O4. Formula Weight: 281.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 259 nm. SMILES: N=C(N(C)C=N1)C2=C1N(C=N2)[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3. InChi Code: InChI=1S/C11H15N5O4/c1-15-3-14-10-6(9(15)12)13-4-16(10)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11-12,17-19H,2H2,1H3/t5-,7-,8-,11-/m1/s1. InChi Key: GFYLSDSUCHVORB-IOSLPCCCSA-N.