1-Ethyl-1-nitrosourea (hydrate)

1-Ethyl-1-nitrosourea (ENU) is a DNA alkylating agent. It increases the concentrations of O6-ethylguanine, N7-ethylguanine, N7-ethyladenine, and N3-ethyladenine in rat brain. ENU (80 mg/kg) is teratogenic in vivo, inducing tumor formation and paw malformations in rat pups when administered to pregnant rats.Formal Name: N-ethyl-N-nitroso-urea, hydrate. Synonyms: ENU, Ethylnitrosourea, N-Ethyl-N-nitrosourea, N-Nitroso-N-ethylurea. Molecular Formula: C3H7N3O2 . XH2O. Formula Weight: 117.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 15 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 3 mg/ml. lambdamax: 240 nm. SMILES: O=NN(CC)C(N)=O. InChi Code: InChI=1S/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7). InChi Key: FUSGACRLAFQQRL-UHFFFAOYSA-N.