1,3,7-Trimethyluric Acid

1,3,7-Trimethyluric acid is a derivative of uric acid (Cay-16219) and a metabolite of caffeine (Cay-14118). It is formed from caffeine by the cytochrome P450 (CYP) isoform CYP3A4. 1,3,7-Trimethyluric acid (500 µM) scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.Formal Name: 7,9-dihydro-1,3,7-trimethyl-1H-purine-2,6,8(3H)-trione. CAS Number: 5415-44-1. Synonyms: 8-oxo Caffeine, NSC 11259, NSC 95858, TMU. Molecular Formula: C8H10N4O3. Formula Weight: 210.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 235, 289 nm. SMILES: O=C(N1)N(C)C2=C1N(C)C(N(C)C2=O)=O. InChi Code: InChI=1S/C8H10N4O3/c1-10-4-5(9-7(10)14)11(2)8(15)12(3)6(4)13/h1-3H3,(H,9,14). InChi Key: BYXCFUMGEBZDDI-UHFFFAOYSA-N.