Rifampicin (3-[4- Methylpiperizinyliminomethyl] rifamycin SV, Rifamycin)

Semisynthetic antibiotic. Antibacerial (tuberculostatic). Inhibits RNA synthesis via RNA Polymerase binding. Specifically inhibits DNA-dependent RNA polymerase in bacteria by forming an inactive complex. Does not affect mammalian RNA polymerase. Synonyms: 3-[[4-Methyl-1-piperazin-yl)imino]methyl]rifamycin, Rifampin, Rifaldazine, Rifamycin AMP, R/AMP, Abrifam, Eremfat, Rifa, CAS No: 13292-46-1, Molecular Formula: C43H58N4O12, Molecular Weight: 822.94, Appearance: Orange to red/brown powder, Purity:, >96.5%, Melting Point: >200°C, Identification: Conforms to IR, Spectrophotometric and Colorimetric analyses, Solubility: Chloroform, DMSO, Alcohol: Insoluble, DMSO: 100mg/ml (121.51mM), Water: Insoluble, pH: 4.5-6.5, Loss on Drying: <1%, Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.