Hygromycin B Powder

Hygromycin B is an aminoglycoside produced by Streptomyces hygroscopicus. The antibiotic interferes with the translation step of polypeptide synthesis of prokaryotes and eukaryotes. The antibiotic inhibits peptide chain elongation by preventing elongation-factor EF-2 dependent translocation. Hygromycin B is used as a selective agent in yeasts, bacterial- and plant cells. The antibiotic is inactivated by means of incorporation of the APH 4 gene. Specifications   Appearance White Crystalline Powder Identification (FTIR) Positive Solubility (100 mg/L) Clear and colourless solution Purity (HPLC) >,92% Potency >,1000 µg/mg Heavy metals <,20 ppm Specific rotation 22.1 Endotoxin <,10 EU/mg Store at 2 - 8°C CAS 31282-04-9" alt="" height="35" />,